optional 1) Apply for or import your existing certificate on the 'Apply For/Manage Your Certificate' tab
see: http://www.ngs.ac.uk/How-to-Join
optional 2) Apply for an NGS account at:
http://www.ngs.ac.uk/How-to-Join
optional 3) Create Grid credentials (known as 'proxy' certificates) used for Grid authentication on the 'Use Certificate' tab.
optional 4) Log-in and get started using the NGS tools at: http://www.ngs.ac.uk/tools/overview